Publications

W.H. Hui, Y.L. Chen, S.W. Chang (2024, Dec).
GraphLOGIC: Lethality prediction of osteogenesis imperfecta on type I collagen by a mechanics-informed graph neural network
International Journal of Biological Macromolecules, Article 139001
(Link)

Y.L. Chen, S.W. Chang (2024, Nov).
Recent advances in the integration of protein mechanics and machine learning
Extreme Mechanics Letters, 72, Article 102236
(Link)

W.T. Chiang, Y.K. Chang, W.H. Hui, S.W. Chang , C.Y. Liao, Y.C. Chang, C.J. Chen, W.C. Wang, C.C. Lai, C.H. Wang, S.Y. Luo, Y.P. Huang, S.H. Chou, T.L. Horng, M.H. Hou, S. P. Muench, R.S. Chen, M.D. Tsai, and N.J. Hu (2024, May).
Structural basis and synergism of ATP and Na+ activation in bacterial K+ uptake system KtrAB
Nature Communications, 15(1), Article 3850
(Link)

W.H. Hui, Y.L. Chen, S.W. Chang (2024, Jan).
Effects of aging and diabetes on the deformation mechanisms and molecular structural characteristics of collagen fibrils under daily activity
International Journal of Biological Macromolecules, 254, Article 127603
(Link)

M.L. Tsai, C.W. Huang, and S.W. Chang (2023, Dec).
Theory-inspired machine learning for stress-strain curve prediction of short fiber-reinforced composites with unseen design space
Extreme Mechanics Letters, 65, Article 102097
(Link)

T.Y. Gong, S.h. Hsu, S.W. Chang, and C.C. Chou (2023, Oct).
Effects of the Degree of Phenol Substitution on Molecular Structures and Properties of Chitosan-Phenol-Based Self-Healing Hydrogels
ACS Biomaterials Science & Engineering, 9(11), 6146-6155
(Link)

M. A. Kuzina, C. M. Kurpiers, Y.Y. Tsai, R. Schwaiger, S.W. Chang, and P. Levkin (2023, Jun).
3D-Printed Inherently Porous Structures with Tetrahedral Lattice Architecture: Experimental and Computational Study of Their Mechanical Behavior
Macromolecular Materials and Engineering, 2300041
(Link)

H.C Hsu, S.R. Lin, H.W. Chen, C.C. Chou, S.W. Chang, and C.W. Huang (2023, Jun).
Machine learning model for preoperative assessment of ultrasound diathermy with implants
International Journal of Thermal Sciences, 193, Article 108499
(Link)

Y.T. Chiang, Y.B. Xiao, S.h. Hsu, S.W. Chang, and C.C. Chou (2023, Apr).
Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9
Computational and Structural Biotechnology Journal, 21, 2792-2800
(Link)

W.H. Hui, P.H. Chiu, I.I. Ng, S.W. Chang, C.C. Chou, and H.H. Chen (2023, Feb).
Unraveling the molecular mechanism of collagen flexibility during physiological warmup using molecular dynamics simulation and machine learning
Computational and Structural Biotechnology Journal, 21, 1630-1638
(Link)

Y.Y. Tsai and S.W. Chang (2022, Oct).
Pullout Strength of Triply Periodic Minimal Surface-Structured Bone Implants
International Journal of Mechanical Sciences,  237, Article 107795
(Link)

Y.Y. Tsai, M.K. Hsieh, P.L. Lai, C.L. Tai, and S.W. Chang (2022, Oct).
Predicting pullout strength of pedicle screws in broken bones from X-ray images
Journal of the Mechanical Behavior of Biomedical Materials, 134, Article 105366
(Link)

Y. Chiang, W.H. Hui, and S.W. Chang (2022, Jul).
Encoding protein dynamic information in graph representation for functional residue identification
Cell Reports Physical Science, 3(7), Article 100975
(Link)

K.C. Yeh, Y.Y. Tsai, and S.W. Chang (2022, Mar).
The Role of Cross-Linkers in the Mechanical Responses of Gold Nanoparticle Assemblies
The Journal of Physical Chemistry C, 126 (14), 6456-6464
(Link)

T.H. Huang, S.h. Hsu, and S.W. Chang (2022).
Molecular interaction mechanisms of glycol chitosan self-healing hydrogel as a drug delivery system for gemcitabine and doxorubicin
Computational and Structural Biotechnology Journal, 20, 700-709
(Link)

Y.Y Tsai and S.W. Chang (2022, Feb).
Size effects of mechanical properties of nanohoneycomb with multiple surface orientations
Mechanics of Materials, 165, 104178
(Link)

Y. Chiang, T.W. Chiu, and S.W. Chang (2022, Jan).
ImageMech: From image to particle spring network for mechanical characterization
Frontiers in Materials, 8, Article 803875
(Link)

K.T. Chen, T.J. Wei, G.C. Li, M.Y. Chen, Y.S. Chen, S.W. Chang, H.W. Yen, and C.S. Chen (2021, Oct).
Mechanical properties and deformation mechanisms in CoCrFeMnNi high entropy alloys: A molecular dynamics study
Materials Chemistry and Physics, 271, 15, Article 124912
(Link)

Y.Y. Lai, D. Li, and S.W. Chang (2021).
Computational insights into the substrate recognition mechanism of cartilage extracellular matrix degradation
Computational and Structural Biotechnology Journal, 19, 5535-5545
(Link)

Y.L. Chen, Y Chiang, P.H. Chiu, I.C. Huang, Y.B. Xiao, S.W. Chang, and C.W. Huang (2021).
High-Dimensional Phase Space Reconstruction with a Convolutional Neural Network for Structural Health Monitoring
Sensors, 21(10), 3514
(Link)

Y.Y. Tsai, Y. Chiang, J.L. Buford, M.L. Tsai, H.C. Chen, and S.W. Chang (2021).
Mechanical and Crack Propagating Behavior of Sierpiński Carpet Composites
ACS Biomaterials Science & Engineering
(Link)

A. Ghimire, Y.Y. Tsai, P.Y. Chen, and S.W. Chang (2021).
Tunable interface hardening: Designing tough bio-inspired composites through 3D printing, testing, and computational validation
Composites Part B: Engineering, 215, 108754
(Link)

Y. Liu, C.W. Wong, S.W. Chang, and S.h. Hsu (2021).
An injectable, self-healing phenol-functionalized chitosan hydrogel with fast gelling property and visible light-crosslinking capability for 3D printing
Acta Biomaterialia, 122, 211-219
(Link)

Y. Chiang and S.W. Chang (2021)
Bridging the gap between NMR measured mean silicate chain length and nano-scale silicate polymorphism of calcium silicate hydrates
Cement and Concrete Research, 140, 106268
(Link)

Y. Chiang, C.C. Tung, X.D. Lin, P.Y. Chen, C.S. Chen, and S.W. Chang (2021)
Geometrically toughening mechanism of cellular composites inspired by Fibonacci lattice in Liquidambar formosana
Composite Structures, 262, 113349
(Link)

J.F. Chang, Y.S. Chou, C.C. Wu, P.C. Chen, W.C. Ko, J.C. Liou, C.Y. Hsieh, W.N. Lin, L.L. Wen, S.W. Chang, T.H. Tung, and T.M. Wang. (2020, Mar)
A Joint Evaluation of Neurohormone Vasopressin-Neurophysin II-Copeptin and Aortic Arch Calcification on Mortality Risks in Hemodialysis Patients
Frontiers in Medicine, 7, Article 102
(Link)

K.L. Chen, D. Li, T.X. Lu, and S.W. Chang (2020, Jan).
Structural Characterization of the CD44 Stem Region for Standard and Cancer-Associated Isoforms
International Journal of Molecular Sciences, 21(1), 336
(Link)

S.C. Hsu, S.h. Hsu, and S.W. Chang (2020).
Effect of pH on Molecular Structures and Network of Glycol Chitosan
ACS Biomaterials Science & Engineering, 6(1), 298-307
(Link)

D. Li, T.H. Kao, and S.W. Chang (2020, Jan).
The structural changes of the mutated ankyrin repeat domain of the human TRPV4 channel alter its ATP binding ability
Journal of the Mechanical Behavior of Biomedical Materials, 101, 103407
(Link)

D. Li and S.W. Chang (2019).
Effects of deformation rate on the unbinding pathway of the MMP8-Aggrecan_IGD complex in cartilage
CMES-Computer Modeling in Engineering & Sciences, 120(2), 305-318
(Link)

J.F. Chang, J.C. Yeh, C.T. Ho, S.H. Liu, C.Y. Hsieh, T.M. Wang, S.W. Chang, I.T. Lee, K.Y. Huang, J.Y. Wang, and W.N. Lin (2019).
Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia
International Journal of Molecular Sciences, 20(18), 4393
(Link)

C.H. Wen, S.C. Hsu, S.H. Hsu, and S.W. Chang (2019, Dec).
Molecular Structures and Mechanisms of Waterborne Biodegradable Polyurethane Nanoparticles
Computational and Structural Biotechnology Journal, 17, 110-117
(Link)

J.C. Yeh, C.C. Wu, C.S. Choy, S.W. Chang, J.C. Liou, K.S. Chen, T.H. Tung, W.N. Lin, C.Y. Hsieh, C.T. Ho, T.M. Wang and J.F. Chang (2018, Nov). Non-Hepatic Alkaline Phosphatase, hs-CRP and Progression of Vertebral Fracture in Patients with Rheumatoid Arthritis: A Population-Based Longitudinal Study
Journal of Clinical Medicine. 7(11), 439
(Link)

W.C. Ko, C.S. Choy, W.N. Lin, S.W. Chang, J.C. Liou, T.H. Tung, C.Y. Hsieh, and J.F. Chang (2018, Sep).
Galectin-3 Interacts with Vascular Cell Adhesion Molecule-1 to Increase Cardiovascular Mortality in Hemodialysis Patients
Journal of Clinical Medicine, 7(10), 300
(Link)

T.H. Huang, C.S. Chen, and S.W. Chang (2018, Feb).
Microcrack patterns control the mechanical strength in the biocomposites
Materials & Design, 140, 505-515
(Link)

S.W. Chang, T.K. Lin, S.Y. Kuo, and T.H. Huang (2017, Dec).
Integration of High-Resolution Laser Displacement Sensors and 3D Printing for Structural Health Monitoring
Sensors, 18(1), 19
(Link)

T.H. Huang, T.H. Huang, Y.S. Lin, C.H. Chang, P.Y. Chen, S.W. Chang, and C.S. Chen (2017, Aug).
Phase-Field Modeling of Microstructural Evolution by Freeze-Casting
Advanced Engineering Materials,  20(3), 1700343
(Link)

C.H. Wu, M.K. Sun, J. Shieh, C.S. Chen, C.W. Huang, C.A. Dai, S.W. Chang, W.S. Chen, and T.H. Young (2017, Apr).
Ultrasound-responsive NIPAM-based hydrogels with tunable profile of controlled release of large molecules
Ultrasonics, 83, 157–163
(Link)

B. An, S.W. Chang, C. Hoop, J. Baum, M. J. Buehler, and D. L. Kaplan (2016, Dec).
Structural Insights into the Glycine Pair Motifs in Type III Collagen
ACS Biomaterials Science and Engineering, 3(3), 269–278
(Link)

T. Li, S.W. Chang, N. Rodriguez-Florez, M. J. Buehler, S. J. Shefelbine, and M. Dao, K. Zeng (2016).
Studies of chain substitution caused sub-fibril level differences in stiffness and ultrastructure of wildtype and oim/oim collagen fibers using multifrequency-AFM and molecular modeling
Biomaterials, 107, 15-22
(Link)

Andriotis, O.G., S.W. Chang, M. Vanleene, P.H. Howarth, D.E. Davies, S.J. Shefelbine, M.J. Buehler, and P.J. Thurner (2015).
Structure–mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model
Journal of the Royal Society Interface, 12(111), 20150701
(Link)

A. Masic, L. Bertinetti, R. Schuetz, S.W. Chang, T.H. Metzger, M.J. Buehler, and P. Fratzl (2015).
Osmotic pressure induced tensile forces in tendon collagen
Nature Communication, 6, 5942 (MIT’s homepage spotlight, January, 2015)
(Link)

S.W. Chang and M.J. Buehler (2014).
Molecular biomechanics of collagen molecules
Materials Today, 17(2), 70-76
(Link)

A. Nair, A. Gautieri, S.W. Chang, and M.J. Buehler (2013).
Molecular mechanics of mineralized collagen fibrils in bone
Nature Communication, 4, 1724 (MIT’s homepage spotlight, April, 2013)
(Link)

S.W. Chang, A. Nair, and M.J. Buehler (2013).
Nanoindentation study of size effects in nickel–graphene nanocomposites
Philosophical Magazine Letters, 93(4), 196-203
(Link)

C.S. Chen, C.C. Chou, and S.W. Chang (2013).
Multiscale analysis of adsorption-induced surface stress of alkanethiol on microcantilever
Journal of Physics D: Applied Physics, 46, 035301 (cover image)
(Link)

S.W. Chang, A. Nair, and M.J. Buehler (2012).
Geometry and temperature effects of the interfacial thermal conductance in copper- and nickel-graphene nanocomposites
Journal of Physics: Condensed Matter, 24(24), 245301
(Link)

S.W. Chang, B. Flynn, J. Ruberti, and M.J. Buehler (2012).
Molecular mechanism of force induced stabilization of collagen against enzymatic breakdown
Biomaterials, 33(15), 3852-3859
(Link)

S.W. Chang, S.J. Shefelbine, and M.J. Buehler (2012).
Structural and mechanical differences between collagen homo- and heterotrimers: General insight and relevance for brittle bone disease
Biophysical Journal, 102(3), 640-648
(Link)

C.S. Chen, S. Kuan, T.H. Chang, C.C. Chou, S.W. Chang, and L.S. Huang (2011).
Microcantilever biosensor: sensing platform, surface characterization, and multiscale modeling
Smart Structures and Systems, 8(1), 17-37
(Link)

C.Y. Chan, Y.Y. Chen, S.W. Chang, and C.S. Chen (2011).
Atomistic Studies of Nanohardness Size Effects
International Journal of Theoretical and Applied Multiscale Mechanics, 2(1), 62-71
(Link)

C.S. Chen, C.C. Chou, S.W. Chang, R.X. Fischer, and H. Schneider (2010).
First-Principles Study on Variation of Lattice Parameters of Mullite Al4+2xSi2-2xO10-x (x=0.125, 0.250, 0.375)
American Mineralogist, 95(11-12), 1617-1623
(Link)

S.W. Chang and C.S. Chen (2008).
A Non-iterative Derivation of the Common Plane for Contact Detection of Polyhedral Blocks
International Journal for Numerical Methods in Engineering, 74(5), 734-753
(Link)